U.S. Department of Health and Human Services, National Institutes of Health Global Health Matters


  AUGUST 2003
In this issue:

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  Symposium shows urgent need for Global Health action
  Message from the Director
  FIC hosts Disease Control Priorities Project for developing countries
  AIDS program promotes research capacity in developing, disadvantaged nations
  FIC spearheads virtual global network for health research
  Fogarty Facts
 
 

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News from the John E. Fogarty International Center

FIC 35th Anniversary Symposium Focuses on Global Health: A Challenge to Scientists

Investing more to improve the health of everyone on the planet is a task that policymakers and biomedicine must tackle, both on humanitarian and self-interest grounds, said speakers at the FIC Symposium on Global Health at the NIH on May 20–21. The need to act has never been more urgent, with such devastating illnesses as malaria, tuberculosis, and AIDS on the rise and the potential for new diseases such as Severe Acute Respiratory Syndrome (SARS) to spread worldwide. As NIH Director Elias Zerhouni, M.D., said at the symposium, which honored FIC's 35th anniversary, the world has become "a village, and we need to energize and synergize our actions around the globe."

Photo: FIC Director Dr. Gerald Keusch addresses symposium attendees.FIC Director Gerald Keusch, M.D., told the symposium attendees that the potential to advance world health has never been better. We are living in extraordinary times given our ability to diagnose, prevent, and treat disease, he said. Despite this, many parts of the world are seeing a decline in life expectancy as people increasingly succumb to infectious and parasitic diseases and to noninfectious ailments such as cardiovascular diseases, injuries, and suicide. "This is just not good enough," said Dr. Keusch, and he added that health policymakers and researchers around the world should cooperate on new and expanded ways to improve health globally. "Each of us can do a great deal when we act alone, but by acting together, we can accomplish an enormous amount," he said.

Children in poorer nations suffer disproportionately from illnesses that are preventable, treatable, or even curable. Kul Gautam, Ph.D., Deputy Executive Director, UNICEF, noted that of every 100 children born, 8 would probably die before their fifth birthday. Daily, 2,000 children die from measles and 4,000 die from simple diarrhea. "These statistics are a cause for shame and outrage," he said. "What is really lacking is not resources, but vision, leadership, and the right priorities."

Public and private sectors spend more than $70 billion annually on health research, yet only 10 percent of the money covers 90 percent of global health problems according to a 1996 World Health Organization report.

Although research organizations such as FIC are working to change this picture by sponsoring projects in over 100 countries, health interests must focus substantially more attention and resources on the developing world, the speakers said.

Honorable Paul G. Rogers, an honorary co-char of the symposium (left), speaks with NIH Director Dr. Elias Zerhouni (right) during the symposium.Not only is the response to current health problems inadequate, new diseases continue to develop and spread around the globe with lightning speed. SARS broke out in rural China and infected people in 28 other countries within months. But SARS also shows what a concerted global response can effect. Addressing the symposium audience, World Health Organization Director-General Gro Harlem Brundtland, M.D., M.P.H., hailed the international community's success at quickly dampening the spread of SARS, saying, "This is global health at its best."

Dr. Brundtland added, "Now we should apply the same energy, same commitment, and necessary resources . . . to curb the threat of less newsworthy public health threats." She added, "We know we must invest more. Global health not only matters; it is the way forward."

Aside from the success at slowing the spread of SARS, health groups have made headway in the past few years in many other areas. For instance, the price of AIDS drugs fell, making them accessible to many more of the afflicted. Policymakers in developed countries, including the Group of Eight industrial democracies, are also giving global health issues more prominence. Also, new world health financing mechanisms are being developed, including the WHO's Global Fund to Fight AIDS, Tuberculosis, and Malaria. The Global Fund attracts and disburses additional resources for these key illnesses via partnerships between governments, the private sector, and affected communities. Since it opened in May 2000, the Fund has raised more than $1.5 billion to cover 153 programs; however, contributions are lagging and approved funds are not being sent to the countries.

Several conference attendees stressed the need to improve world health as a means to economic development. Harold Varmus, M.D., former NIH Director and now President at the Memorial Sloan-Kettering Cancer Center, said that in the past couple of years "there has been an increased appreciation that better health can be a determinant of economic improvement." Especially in developing countries, making people healthier is an effective way of aiding the economy, for instance, by avoiding lost workdays and raising the energy levels of workers.

Dr. Varmus said advancing health in developing nations will require additional resources, including imaginative new programs supported by both governments and private groups, well-financed centers for conducting research, improved communication, free distribution of scientific literature, and a global science corps of senior researchers willing to spend a year or two in a developing country research institution to help improve the way science is conducted.

FIC supports research in priority global health areas and also develops human capital and research capacity in the poorest nations of the world. Many speakers called for the establishment of more centers in afflicted nations and further training of local people. Sir David Weatherall, M.D., F.R.C.P., Emeritus Regius Professor of Medicine at the University of Oxford and Fogarty Scholar in Residence, said this task of bringing health research to developing nations would not be easy. "It's very difficult for outsiders to go into any country with a recipe of what should be done. It has to be a very gradual process."

From left to right:  Dr. Richard Feachem, Global Fund for AIDS, TB, Malaria; Dr. Gerald T. Keusch, FIC Director; Dr. Harvey Fineberg, Institute of Medicine; Dr. Kul Gautam, UNICEF (partially hidden); Ms. Mary Woolley, Research!America; the Honorable Paul G. Rogers; and the Honorable Louis Sullivan.This sentiment was echoed by William Makgoba, Ph.D., Former President, South African Medical Research Council, and currently Vice Chancellor at the University of Natal, who stressed the need for western organizations to initiate partnerships with developing countries to ensure that western scientists understand the culture, language, and needs of the host nation.

Some speakers called for more efficient delivery systems, for instance, ensuring that pharmaceutical drugs do not end up on the black market. Other speakers emphasized the need to reward intellectual property rights, encourage more private participation, and foster increased cross-discipline research.

The symposium attendees congratulated FIC on its achievements during the past 35 years and hailed Congressman John E. Fogarty of Rhode Island—after whom the center is named—for championing imaginative health legislation and promoting an international research agenda. James Crowley, M.D., Professor of Medicine at Brown University, who knew Fogarty in his childhood, spoke of the lawmaker's vision. "In 1947, Fogarty became convinced that the promotion of world health by the U.S. should be the paramount goal of our foreign policy," a position that was not popular in those days, although it is more widely understood today.

Dr. Crowley added that the legislation Fogarty promoted before his death at age 53 "has had a profound effect on extending the lives and improving the health of people in this country and around the world. The world owes him a great debt of gratitude."

We are interested in hearing from you. Please feel free to contact Irene Edwards at edwardsi@mail.nih.gov.

 

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